SEX DIFFERENCES IN THE LEVELS OF MARKERS OF ENDOGENOUS INTOXICATION IN RATS WITH EXPERIMENTAL OBESITY UNDER CONDITION OF PREVENTIVE ADMINISTRATION OF ORLISTAT AND BIONANOCOMPOSITE BASED ON FENUGREEK

Obesity is a complex disease involving an excessive amount of body fat. generally caused by eating too much and physical activity little. High-calorie diet-induced obesity occurs in both sexes, but more pronounced changes blood parameters associated with this are common men. However, the gender-specific mechanisms development little known. Therefore, purpose our study was to determine sex-specific response content middle mass molecules oligopeptides serum rats under conditions highcalorie diet consumption after administration bionanocomposite based on fenugreek orlistat. To do this, we used modified Gabrielian method mathematical processing statistical analysis results.